Results: 628

For: randomised controlled trial

Opening ward doors doesn’t make staff any more coercive

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John Baker summarises a new Norwegian trial published last week, which compares an open-door policy to treatment-as-usual in urban psychiatric inpatient wards.

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Risk factors for depression relapse while on long-term maintenance antidepressant treatment

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In her debut blog, Asha Ladwa discusses a secondary analysis of data from the ANTLER trial, which investigated the clinical factors associated with relapse in primary care patients on long-term maintenance antidepressants.

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SMS CBT TLC CYP? 🤔 Does delivering cognitive behavioural therapy via text messages help improve depression in young people?

Young,Smiling,Woman,Wearing,Glasses,Holding,Smartphone,Using,Cellphone,Modern

Becky Appleton summarises a randomised controlled trial investigating the effectiveness and acceptability of text-based Cognitive Behavioural Therapy for improving depression in young adults.

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Early intervention for psychosis: better outcomes in the short term?

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Emanuele Osimo blogs about the 20-year follow up of the OPUS trial, which tested early intervention services for people with first-episode schizophrenia spectrum disorder.

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Reducing stigma and sickness absence: can a low intensity psychological intervention help us ‘Prevail’?

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Emmeline Lagunes-Cordoba summarises a cluster randomised controlled trial exploring the effectiveness of a low-intensity psychological intervention to reduce mental health stigma and improve help-seeking in the workplace.

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Guided self-help for anxiety: the importance of choice

Only 7% of the participants accepted being randomised, while 93% chose their treatment, showing a preference for CAT-GSH; however, CAT-GSH and CBT-GSH were found to result in similar anxiety outcomes at the follow-up assessments.

In her latest blog, Francesca Zecchinato summarises findings from a recent pragmatic, partially randomised, patient preference trial on two forms of guided self-help for anxiety.

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Brief interpersonal therapy may help relieve maternal depression during pregnancy

a pregnant woman in a grey top makes a heart shape with her hands over her pregnancy bump

In this blog, Francesca Kingston summaries a clinical trial from the US Care Project, which investigated whether depression can be reduced during pregnancy and before birth using a brief, safe intervention.

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High-fluoride toothpaste or high fluoride mouthrinse to prevent white spot lesions in adolescent orthodontic patients – trial

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270 pateints were randomised in this trial to compare high-fluoride toothpaste and high-fluoride mouth rinse for preventing white spot lesions during orthodontic treatment. The findings suggest a benefit for high fluoride toothpaste and fluoride mouth rinse in preventing white spot lesions.

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The Body Project peer-led eating disorders prevention programme shows promise for bulimia nervosa and purging disorder

Across the three trials, 10.6% of Body Project participants went on to develop an eating disorder in comparison to 17.4% of the control groups, indicating promise in the intervention.

Georgie Parker summarises a recent study which outlines the results of three trials exploring the effectiveness of a peer-led dissonance-based programme for preventing the onset of eating disorders.

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Manual v powered toothbrushing in adolescent orthodontic patients – trial

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The aim of this randomised trial was to compare the efficacy of a powered versus manual toothbrush in controlling plaque and gingival health in participants undergoing fixed orthodontic treatment in respect of both the short term and long term. The findings showed no differences between the brush types at any time points ( 1, 6 or 12 months).

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